weak D type 49

Structure

RHD(S257F)

Key changes from standard allele

770C>T (S257F)

ISBT allele designation

RHD*01W.49
RHD*weak D type 49

Nucleotide changes relative to "standard RHD"

c.770 C>T

Amino acid changes relative to standard protein

Ser to Phe at codon 257

S257F

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2006 AM181333 (submitted 2006-01-09, released 2006-01-12)

First full publication: 2007 Polin H et. al. Transfusion. 2007 Aug;47(8):1350-5.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

AM181333

Observations

Linz region: Polin H et. al. Transfusion. 2007 Aug;47(8):1350-5.

Related Alleles

RHD(K189N,S257F) [RHD(K189N,S257F)]

Additional comments

Last update: 2012-03-27 (yyyy-MM-dd)