weak D type 44

Structure

RHD(Y243C)

Key changes from standard allele

728A>G (Y243C)

ISBT allele designation

RHD*01W.44
RHD*weak D type 44

Nucleotide changes relative to "standard RHD"

728 A>G

Amino acid changes relative to standard protein

Tyr to Cys at codon 243

Y243C

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2004 AJ867386 (submitted 2004-12-03, released 2004-12-07)

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

weak D expression: direct agglutination negative, IAT 1+ Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Observations

Japan (general): 1 of 45 samples with weak D phenotype ccDEe Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Additional comments

Last update: 2017-02-19 (yyyy-MM-dd)