weak D type 38

Structure

RHD(G278D)

Key changes from standard allele

833G>A (G278D)

ISBT allele designation

RHD*01W.38
RHD*weak D type 38

Nucleotide changes relative to "standard RHD"

c.833 G>A

Amino acid changes relative to standard protein

Gly to Asp at codon 278

G278D

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2003 AY449381 (submitted 2003-10-15, released 2003-12-03)

First full publication: 2004 Ansart-Pirenne H et. al. Transfusion. 2004 Sep;44(9):1282-6.

Serology

No data

Observations

Brazil (general): 21 of 369 samples with atypical D expression; Ce-associated Arnoni CP et. al. Transfusion. 2014 Apr;54(4):962-9. doi: 10.1111/trf.12557. Epub 2014 Feb 28.

Additional comments

Last update: 2018-02-19 (yyyy-MM-dd)