weak D type 20

Structure

RHD(F417S)

Key changes from standard allele

1250T>C (F417S)

ISBT allele designation

RHD*01W.20
RHD*weak D type 20

Nucleotide changes relative to "standard RHD"

1250 T>C

Amino acid changes relative to standard protein

Phe to Ser at codon 417

F417S

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First mention in abstract form: 2000 Witter B, thesis

First full publication: 2006 Yu X et. al. Transfusion. 2006 Aug;46(8):1343-51.

ISBT group

weak D

Phenotype characterization and grouping

weak D type

Serology

Rhesus Index 0.56 Yu X et. al. Transfusion. 2006 Aug;46(8):1343-51.

Observations

South-Western Germany: Yu X et. al. Transfusion. 2006 Aug;46(8):1343-51.

Additional comments

Multiple samples known

Last update: 2012-03-25 (yyyy-MM-dd)