weak D type 16

Structure

RHD(W220R)

Key changes from standard allele

658T>C (W220R)

ISBT allele designation

RHD*01W.16
RHD*weak D type 16

Nucleotide changes relative to "standard RHD"

658 T>C

Amino acid changes relative to standard protein

Trp to Arg at codon 220

W220R

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1999 Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Rhesus Index 0.44 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.

Observations

South-Western Germany: Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)