weak D type 12

Structure

RHD(G277E)

Key changes from standard allele

830G>A (G277E)

ISBT allele designation

RHD*01W.12
RHD*weak D type 12

Nucleotide changes relative to "standard RHD"

830 G>A

Amino acid changes relative to standard protein

Gly to Glu at codon 277

G277E

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1999 Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.

Observations

South-Western Germany: Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)