RHD-ceAG.05(2)-D

Structure

RHD-RHCE(2)-RHD(A85G)

Key changes from standard allele

254C>G (A85G)
744C>T
Hybrid RHCE(2)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.[150 T>C;178 A>C;201 G>A;203 G>A;254 C>G;307 T>C;744 C>T]

Amino acid changes relative to standard protein

, I60L, S68N, A85G, S103P

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2017 KY926709 (submitted 2017-04-10, released 2017-07-22)

ISBT group

Phenotype characterization and grouping

Serology

No data

Observations

No data

Additional comments

RHD exon 2 is replaced by RHCE sequence derived from a ceAG allele. In addition, there is a silent 744 C>T substitution in the sequence (not commented by the author)

Last update: 2018-02-06 (yyyy-MM-dd)