weak D type 106

Structure

RHD(W74G)

Key changes from standard allele

220T>G (W74G)

ISBT allele designation

RHD* 01W.106
RHD*weak D type 106

Nucleotide changes relative to "standard RHD"

220 T>G

Amino acid changes relative to standard protein

Trp to Gly at codon 74

W74G

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC053437 (submitted 2015-04-28, released 2015-06-04)

First full publication: 2015 Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

weakened D expression: direct agglutination 2+, IAT 4+ Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Observations

Japan (general): 1 of 45 samples with weakened D expression Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Additional comments

Last update: 2017-02-12 (yyyy-MM-dd)