weak D type 10.2

Structure

RHD(W393R,K400T)

Key changes from standard allele

1177T>C (W393R)
1199A>C (K400T)

ISBT allele designation

RHD*01W.10.2
RHD*weak D type 10.2

Nucleotide changes relative to "standard RHD"

1177 T>C, 1199 A>C

Amino acid changes relative to standard protein

W393R, K400T

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC075281 (submitted 2015-08-17, released 2015-09-08)

First full publication: 2016 Isa K et. al. Vox Sang. 2016 Oct;111(3):315-319. doi: 10.1111/vox.12413. Epub 2016 May 17.

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weak D LC075281
weak D Isa K et. al. Vox Sang. 2016 Oct;111(3):315-319. doi: 10.1111/vox.12413. Epub 2016 May 17.

Observations

Japan (general): LC075281
USA (general): KT870131

Additional comments

Last update: 2017-01-29 (yyyy-MM-dd)