RHD(V238L,V270G)

Structure

RHD(V238L,V270G)

Key changes from standard allele

712G>C (V238L)
809T>G (V270G)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

712 G>C, 809 T>G

Amino acid changes relative to standard protein

V238L, V270G

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 2012 Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64. (submitted 2011-04-19, released 2011-09-29)

ISBT group

Phenotype characterization and grouping

D positive (no further data)

Serology

Discrepant results with different anti-D Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64.

Observations

France (general): Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64.
France (general): One of 256 weak D type 1-like samples Raud L et. al. Transfus Med. 2017 Nov 22. doi: 10.1111/tme.12485.

Additional comments

Last update: 2017-12-05 (yyyy-MM-dd)