weak D type 105

Structure

RHD(S67W)

Key changes from standard allele

200C>G (S67W)

ISBT allele designation

RHD* 01W.105
RHD*weak D type 105

Nucleotide changes relative to "standard RHD"

c.200 C>G

Amino acid changes relative to standard protein

Ser to Trp at codon 67

S67W

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC053436 (submitted 2015-04-28, released 2015-06-04)

First full publication: 2015 Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Other relevant descriptions:
KU363607 (submitted 2015-12-29, released 2016-03-12)

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Weakened D expression. Direct agglutination negative, IAT 1+ Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Observations

Japan (general): 1 of 45 samples with weakened D phenotype Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Additional comments

Observed in ccDEe sample

Last update: 2017-02-12 (yyyy-MM-dd)