weak D type 3.1

Structure

RHD(S3C,I60L)

Key changes from standard allele

178A>C (I60L)
8C>G (S3C)

ISBT allele designation

RHD*01W.3.1
RHD*weak D type 3.1

Nucleotide changes relative to "standard RHD"

8 C>G, 178 A>C

Amino acid changes relative to standard protein

S3C, I60L

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2014 KF861930 (submitted 2013-11-15, released 2014-02-15)

First full publication: 2014 Garcia F et. al. Transfusion. 2015 Feb;55(2):427-9.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

weak D Garcia F et. al. Transfusion. 2015 Feb;55(2):427-9.

Observations

Spain (general): Garcia F et. al. Transfusion. 2015 Feb;55(2):427-9.
France (general): Not detected among 32 weak D type 3-like samples Raud L et. al. Transfus Med. 2017 Nov 22. doi: 10.1111/tme.12485.

Additional comments

Haplotype DCe or Dce

Last update: 2017-12-05 (yyyy-MM-dd)