weak D type 153

Structure

RHD(S122W)

Key changes from standard allele

365C>G (S122W)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.365 C>G

Amino acid changes relative to standard protein

Ser to Trp at codon 122

S122W

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2011 JF816276 (submitted 2011-04-18, released 2011-10-09)

First full publication: 2012 Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64. (submitted 2011-04-19, released 2011-09-29)

ISBT group

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Discrepant results with different anti-D Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64.
weak D phenotype Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

Observations

France (general): Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64.
India (general): Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

Additional comments

Last update: 2018-05-23 (yyyy-MM-dd)