RHD(Q41X)

Structure

RHD(Q41X)

Key changes from standard allele

121C>T (Q41X)
643T>C (F215L)
646T>C
988T>C (Y330H)

ISBT allele designation

RHD*01N.09

Nucleotide changes relative to "standard RHD"

c.[121 C>T;643 T>C;646 T>C;988 T>C]

Amino acid changes relative to standard protein

Q41X, F215L, L216L, Y330H

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1997 Avent ND et. al. Blood. 1997 Apr 1;89(7):2568-77.

ISBT group

RHD negative

Phenotype characterization and grouping

D negative

Serology

No data

Observations

No data

Additional comments

The mutations 3´of the STOP codon 41 do not have any influence on the phenotype

Last update: 2012-03-25 (yyyy-MM-dd)