weak D type 148

Structure

RHD(N224D)

Key changes from standard allele

670A>G (N224D)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.670 A>G

Amino acid changes relative to standard protein

Asn to Asp at codon 224

N224D

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2013 KF142384 (submitted 2013-05-22, released 2013-09-18)

First full publication: 2014 He J et. al. Transfusion. 2015 Jan;55(1):137-43. doi: 10.1111/trf.12797. Epub 2014 Jul 29.

ISBT group

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weak D phenotype He J et. al. Transfusion. 2015 Jan;55(1):137-43. doi: 10.1111/trf.12797. Epub 2014 Jul 29.

Observations

China (general): KF142384

Additional comments

Last update: 2018-05-23 (yyyy-MM-dd)