weak D type 115

Structure

RHD(M328K)

Key changes from standard allele

983T>A (M328K)

ISBT allele designation

RHD* 01W.115
RHD*weak D type 115

Nucleotide changes relative to "standard RHD"

983 T>A

Amino acid changes relative to standard protein

Met to Lys at codon 328

M328K

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC053446 (submitted 2015-04-28, released 2015-06-04)

First full publication: 2015 Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weakened D expression: direct agglutination 3+, IAT 4+ Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Observations

African ancestry (general): 2 of 45 samples with weakened D expression Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Additional comments

Last update: 2017-02-12 (yyyy-MM-dd)