weak D type 94

Structure

RHD(M295T)

Key changes from standard allele

884T>C (M295T)

ISBT allele designation

RHD* 01W.94
RHD*weak D type 94
RHD*01EL.46
RHD*DEL46

Nucleotide changes relative to "standard RHD"

884 T>C

Amino acid changes relative to standard protein

Met to Thr at codon 295

M295T

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2012 HE861896 (submitted 2012-06-14, released 2012-07-02)

First full publication: 2013 Pham BN et. al. Immunohematology. 2013;29(2):55-62.

Other relevant descriptions:
LC075280 (submitted 2015-08-17, released 2015-09-08)

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

weak D Pham BN et. al. Immunohematology. 2013;29(2):55-62.

Observations

Switzerland (general): Ich habe noch folgende Angabe für Sie. Wir haben unterdessen 4 Spender mit einem M295T gefunden. Alle haben den Phänotyp CcD.ee. Mit freundlichen Grüssen Hein Hustinx Hustinx H Observation of RHD(M295T) (personal communication)
France (general): Pham BN et. al. Immunohematology. 2013;29(2):55-62.
Japan (general): LC075280

Additional comments

Reported haplotypes: CDe (Pham) and cDE (Ogasawara).

Last update: 2017-02-18 (yyyy-MM-dd)