RHD(M1T)

Structure

RHD(M1T)

Key changes from standard allele

2T>C (M1T)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.2 T>C

Amino acid changes relative to standard protein

Met to Thr at codon 1

M1T

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC053435 (submitted 2015-04-28, released 2015-06-04)

First full publication: 2015 Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

ISBT group

Phenotype characterization and grouping

Serology

weakened D expression: direct agglutination negative; IAT 3+ Colin Y et. al. Blood. 1991 Nov 15;78(10):2747-52.

Observations

Japan (general): 1 of 45 samples with weakened D expression Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Additional comments

Last update: 2015-10-18 (yyyy-MM-dd)