weak D type 154

Structure

RHD(L216F)

Key changes from standard allele

648G>C (L216F)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.648 G>C

Amino acid changes relative to standard protein

Leu to Phe at codon 216

L216F

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2012 JQ405073 (submitted 2012-01-09, released 2012-04-21)

Other relevant descriptions:
Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

ISBT group

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weak D phenotype Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

Observations

India (general): 2 of 223 weak D samples Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

Additional comments

Last update: 2018-05-23 (yyyy-MM-dd)