weak D type 102

Structure

RHD(I25F)

Key changes from standard allele

73A>T (I25F)

ISBT allele designation

RHD* 01W.102
RHD*weak D type 102

Nucleotide changes relative to "standard RHD"

73 A>T

Amino acid changes relative to standard protein

Ile to Phe at codon 25

I25F

Haplotype (typical)

multiple

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC075264 (submitted 2015-08-17, released 2015-09-08)

Other relevant descriptions:
KU363604 (submitted 2015-12-29, released 2016-03-12)
LN999838 (submitted 2015-12-18, released 2016-01-30)
Filosa L et. al. Transfusion. 2016 May 18. doi: 10.1111/trf.13655.

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weak D LC075264
ccDee sample Filosa L et. al. Transfusion. 2016 May 18. doi: 10.1111/trf.13655.
Direct agglutination 2+, AGT 4+ Isa K et. al. Vox Sang. 2016 May 17. doi: 10.1111/vox.12413.

Observations

Japan (general): LC075264
Japan (general): Isa K et. al. Vox Sang. 2016 May 17. doi: 10.1111/vox.12413.

Additional comments

Haplotype seemingly cDe (Filosa L et al. 2016) or cDE (Isa K et al. 2016)

Last update: 2017-02-12 (yyyy-MM-dd)