weak D type 152

Structure

RHD(G63C)

Key changes from standard allele

187G>T (G63C)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.187 G>T

Amino acid changes relative to standard protein

Gly to Cys at codon 63

G63C

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2018 MG190348 (submitted 2017-10-03, released 2018-03-17)

First full publication: 2018 Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

ISBT group

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

weak D phenotype Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

Observations

African ancestry (general): 3 of 223 weak D samples Fichou Y et. al. Transfusion. 2018 Feb 25. doi: 10.1111/trf.14552.

Additional comments

Last update: 2018-05-23 (yyyy-MM-dd)