weak D type 112

Structure

RHD(G212D)

Key changes from standard allele

635G>A (G212D)

ISBT allele designation

RHD* 01W.112
RHD*weak D type 112

Nucleotide changes relative to "standard RHD"

635 G>A

Amino acid changes relative to standard protein

Gly to Asp at codon 212

G212D

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC053442 (submitted 2015-04-28, released 2015-06-04)

First full publication: 2015 Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Other relevant descriptions:
KT803991 (submitted 2015-09-23, released 2016-03-05)

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weak D phenotype: direct agglutination negative, IAT 2+ Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Observations

Japan (general): 1 of 45 samples with weak D phenotype; CcDee Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Additional comments

Last update: 2017-02-12 (yyyy-MM-dd)