weak D type 78

Structure

RHD(F410V)

Key changes from standard allele

1228T>G (F410V)

ISBT allele designation

RHD* 01W.78
RHD*weak D type 78

Nucleotide changes relative to "standard RHD"

c.1228 T>G

Amino acid changes relative to standard protein

Phe to Val at codon 410

F410V

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First mention in abstract form: 2009 Vege S & et al. Transfusion 2009;49: SP172.

First submission to GenBank: 2010 FN908868 (submitted 2010-06-14, released 2010-06-15)

First full publication: 2011 Silvy M et. al. Transfusion. 2011 Feb;51(2):401-11.

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

Silvy M et. al. Transfusion. 2012 Feb 10.

Observations

France (general): Silvy M et. al. Transfusion. 2011 Feb;51(2):401-11.
France (general): 2 samples CcDee Silvy M et. al. Transfusion. 2012 Feb 10.

Additional comments

Last update: 2017-02-12 (yyyy-MM-dd)