RHD(F223V,G278V)

Structure

RHD(F223V,G278V)

Key changes from standard allele

667T>G (F223V)
833G>T (G278V)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.[667 T>G;833 G>T]

Amino acid changes relative to standard protein

F223V, G278V

Haplotype (typical)

not reported

Allele cluster

weak D type 4 cluster

Descriptions

First full publication: 2012 Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64. (submitted 2011-04-19, released 2011-09-29)

ISBT group

Phenotype characterization and grouping

D positive (no further data)

Serology

Discrepant results with different anti-D Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64.

Observations

France (general): Fichou Y et. al. Transfusion. 2012 Apr;52(4):759-64.

Additional comments

Last update: 2012-05-07 (yyyy-MM-dd)