RHD(D53Y)

Structure

RHD(D53Y)

Key changes from standard allele

157G>T (D53Y)

ISBT allele designation

RHD* 01W.104
RHD*weak D type 104

Nucleotide changes relative to "standard RHD"

157 G>T

Amino acid changes relative to standard protein

Asp to Tyr at codon 53

D53Y

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC075266 (submitted 2015-08-17, released 2015-09-08)

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression

Serology

weak D LC075266

Observations

Japan (general): LC075266

Additional comments

From 3-Jan-17 to 19-Feb-17 this allele was listed as "weak D type 104". However, the substituion is likely extracellular and a partial D phenotype is more likely (but not yet proven).

Last update: 2017-02-19 (yyyy-MM-dd)