RHD(165C>T)

Structure

RHD(165C>T)

Key changes from standard allele

165C>T

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.165 C>T

Amino acid changes relative to standard protein

ISBT group

Phenotype characterization and grouping

D positive (apparently normal); weakened D expression

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

Other relevant descriptions:
DQ309583 (submitted 2005-11-30, released 2006-04-01)

Serology

weak antigen D DQ309583
Normal antigen D density FN545815

Observations

Austria (general): FN545815
China (general): DQ309583
Tibetan: Observed in trans to normal RHD AM398143

Related Alleles

weak D type 68 [RHD(165C>T,1213C>G)]

Additional comments

The cause of the reduced antigen D expression in the first observation remains unknown; the silent 165C>T mutation was observed in a sample of normal antigen D density, too.

Last update: 2012-03-25 (yyyy-MM-dd)