DBO-2

Structure

RHD(357T>C)

Key changes from standard allele

357T>C

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.357 T>C

Amino acid changes relative to standard protein

not applicable

ISBT group

Phenotype characterization and grouping

weakened D expression

Phenotypes observed

cDEe (major)

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First mention in abstract form: 2006 Wei Q (thesis) Ulm 2006

First submission to GenBank: 2007 AM398144 (submitted 2006-08-30, released 2007-07-31)

Other relevant descriptions:
JF274263 (submitted 2011-01-30, released 2011-08-03)
KX929317 (submitted 2016-10-03, released 2017-09-30)

Serology

weak expression of antigen D JF274263
weak D phenotype KX929317
weakened D expression Ye SH et. al. Blood Transfus. 2014 Jul;12(3):396-404. doi: 10.2450/2013.0121-13. Epub 2013 Dec

Observations

China (general): KX929317
Tibetan: Wei Q (thesis) Ulm 2006
Xian: 1 of 2493 samples D negative in saline Ye SH et. al. Blood Transfus. 2014 Jul;12(3):396-404. doi: 10.2450/2013.0121-13. Epub 2013 Dec

Additional comments

Last update: 2018-02-19 (yyyy-MM-dd)